09:00 – 09:45

Invited Lecture

Chairperson: Low-Tone Ho (Taiwan)

Mitochondrial Paradigm for Degenerative Diseases, Aging and Cancer: Ancient Origins and Mitochondrial Diseases

Douglas C. Wallace (U.S.A.)

09:45 – 10:30

Oral Presentations II: β Cell Regeneration, MODY and Type 1 Diabetes

Chairpersons: Hong Kyu Lee (Korea)

  Elizabeth Paz-Pacheco (Philippines)

OP-4

OP-5

OP-6

Exendin-4 upregulates the expression of PDX-1 and Ngn3 during pancreatic b-cell regeneration in streptozotocin-treated mice.

Tetsushi Toyonaga (Japan)

Studies of the genetic variability of the Pax4, Nkx6.1 and Nkx2.2 genes in Thai with maturity onset diabetes of the young (MODY)

Nattachet Plengvidhaya (Thailand)

CBLB gene and Type 1 diabetes (T1D) in children

Yann-Jinn Lee (Taiwan)

10:30-10:45

Coffee break (Poster Discussion)

10:45–11:30

Oral Presentations III: Genetic Epidemiology and AICAR  

Chairpersons:Eiichi Araki (Japan)

Tjin-Shing Jap (Taiwan)

OP-7

Association between Polymorphisms in the Nuclear Respiratory Factor 1 Gene and Type 2 Diabetes Mellitus in the Korean Population

Young Min Cho (Korea)

           OP-8

The role of plasma membrane type sialidase gene NEU3 and GM3 synthase gene GM3S (SIAT9) on the pathogenesis of type 2 diabetes mellitus in Japanese.

Susumu Suzuki(Japan)

           OP-9

AICAR down regulates the expression of insulin receptor in HepG2 cells.

Kazuya Matsumoto (Japan)

11:30 – 12:00

Oral Presentations IV: Insulin sensitivity and Diabetic nephropathy

Chairpersons:Juliana Chan (Hong Kong)

Shyi-Jang Shin (Taiwan)

OP-10

Prognostic Effect of Insertion/Deletion Polymorphism of Angiotensin-Converting Enzyme Gene on Renal and Cardiovascular Clinical Outcomes in Chinese Type 2 Diabetic Patients

Wing Yee So(Hong Kong)

OP-11

Is there inter-ethnic variation in genetic susceptibility to diabetic nephropathy?

Daniel P K Ng (Singapore)

12:00 – 12:05

Closing Remarks from Chairman of the Study Group on Molecular Diabetology in Asia

Kishio Nanjo (Japan)

Posters

P-1 Protective effects of eugenol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells

Hsiu-Chung Ou (Taiwan)

P-2 Molecular study on congenital hyperinsulinemia- hyperammonemia syndrome in a family

Hsin-Jung Li (Taiwan)

P-3 Increased Oxidative Damage with Altered Antioxidative Status in Type 2 Diabetic Patients Harboring the 16189 T to C Variant of Mitochondrial DNA

Pei-Wen Wang (Taiwan)

P-4 Effect of chromium chloride GTF milk powder supplement on gene expression of insulin signaling molecules in KK/HlJ diabetic mice

Tong-Yuan Tai (Taiwan)

P-5The approaches to overcome islet graft failureJyuhn-Huarng Juang(Taiwan)

P-6Changes of Circulating Vascular Adhesion Protein-1 Correlate Negatively with the Changes in Waist Circumference and Diastolic Blood Pressure after Gastric Partition Surgery for Morbid Obesity

Hung-Yuan Li (Taiwan)

P-7Angiotensin converting enzyme gene polymorphism and diagetic nephropathy in Filipino type 2 diavetes mellirus patients

Elizabete Paz Pacheco (Philippines)